On a stormy winter night in 1964, Dr. David Henry makes a decision that will forever change the lives of two families. During an emergency delivery, David welcomes his son, a healthy boy, and a daughter diagnosed with Down's syndrome. In a moment of panic and perceived mercy, he sends his daughter away, convincing his wife of their loss. Caroline Gill, the attending nurse, makes the opposite choice, embarking on a journey to raise the child as her own. As years pass, the secret simmers beneath the surfaces of their lives, threading a path of deception, love, and eventual revelation. 'The Memory Keeper's Daughter' delves into the complex tapestry of human relationships, the nature of family, and the ripple effects of a single lie.